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HRID1255394

反应详情

EQUATION

反应方程式

HRID 1255394 的结构方程式

REACTANTS

反应物

2
结构：O=C(O)c1ccc2cccnc2n1
HCID735156

1,8-Naphthyridine-2-carboxylic acid

C9H6N2O2

结构：CCOC(=O)c1cc2cc(F)c(C(C)(F)F)nc2nc1C(F)(F)F
HCID86650156

未命名化合物

PRODUCTS

生成物

1
结构：CC(F)(F)c1nc2nc(C(F)(F)F)c(C(=O)O)cc2cc1F
HCID86650155

未命名化合物

PROCEDURE

实验过程

In a similar procedure to Example 1, Stage 2, ethyl 7-(1,1-difluoroethyl)-6-fluoro-2-trifluoromethyl-[1,8]-naphthyridine-3-carboxylate was hydrolysed to the required naphthyridine carboxylic acid as a colourless solid. 1H NMR (CDCl3) δ: 9.15 (1H, s), 8.80 (1H, d), 2.20 (3H, t). Molecular ion: (MH)+325.)