HCID 66602031, compound → HCID 66602246, compound

HRID 1255401Notes

Reaction equation

HRID 1255401 reaction equation
[CH:1]12[O:8][CH:5]([CH:6]=[CH:7]1)[C:4](=[O:9])[CH2:3][C:2]2=[O:10]>C(O)C.[Pd]>[CH:5]12[O:8][CH:1]([CH2:7][CH2:6]1)[C:2](=[O:10])[CH2:3][C:4]2=[O:9]

Participants

4

Reactant 1

HCID 66602031HCID 66602031, compound

Product 1

HCID 66602246HCID 66602246, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

To a stirred solution of 8-oxa-bicyclo[3.2.1]oct-6-ene-2,4-dione (5.1 g) in ethanol (100 ml) was added palladium on charcoal (0.51 g, 5% by wt. catalyst) and the mixture hydrogenated at ambient temperature and pressure over 6 hours. The catalyst was removed by filtration and the solvent evaporated under reduced pressure to afford the required product containing some ethyl enolether of the required product.

Workup

  1. customThe catalyst was removed by filtration
  2. customthe solvent evaporated under reduced pressure

Sources & evidence

ORD record
ord-5e9564f0657846d389ed0fb704e002ba
Source dataset
uspto-grants-2013_06
Patent number
US08461083B2

Reaction notes

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