2-Aminopyridine → HCID 136052974, compound

Participants

Reaction Conditions

Reaction Steps

2-aminopyridine (996 mg, 10.58 mmol) and diethyl allylmalonate (2098 μl, 10.58 mmol) were combined and heated to 160° C. neat for 9 hours. The brown solution solidified upon cooling to room temperature. The solid was filtered and washed with Et2O to yield the title compound as a tan solid (580 mg, 27%) LCMS (ES+) m/z 203.02 (M+H)+.

Provenance & Evidence