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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1255925Generated: November 2, 2026

Trimethylsilylacetylene → HCID 178437114, compound

https://huagongshe.com/reaction/1255925

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrimethylsilylacetyleneHCID 66111—
ReactantHCID 178419455HCID 178419455—
ProductHCID 178437114HCID 178437114—

Reaction Steps

The title compound can be synthesized from 7-ethynyl-1H-imidazo[4,5-c]pyridine and 3-iodo-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl) benzamide in a manner similar to that described for Example 1. 7-ethynyl-1H-imidazo[4,5-c]pyridine is prepared from 7-bromo-1H-Imidazo[4,5-c]pyridine and ethynyltrimethylsilane according to the 2 steps procedure described in Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08461167B2
Source datasetuspto-grants-2013_06
ORD IDord-fe8e71c150624284bee0293df43d5487
Source noteuspto-grants-2013_06