Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1255979Generated: October 26, 2026

2-{2-[2-(2-[4-(4,5-Dichloro-2-fluoro-phenylamino)-6-nitro-quinazoline-7-yloxy]-ethoxy]-ethoxy}-ethoxy)-ethanol → n4-(4,5-Dichloro-2-fluoro-phenyl)-(2-{2-[2-(2-ethoxy)-ethoxy]-ethoxy}-ethoxy)-quinazoline-4,6-diamine

https://huagongshe.com/reaction/1255979

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-{2-[2-(2-[4-(4,5-Dichloro-2-fluoro-phenylamino)-6-nitro-quinazoline-7-yloxy]-ethoxy]-ethoxy}-ethoxy)-ethanolHCID 69319925—
ReactantN4-(4,5-dichloro-2-fluoro-phenyl)-7-[2-ethoxy-ethoxy]-quinazoline-4,6-diamineHCID 69320196—
Productn4-(4,5-Dichloro-2-fluoro-phenyl)-(2-{2-[2-(2-ethoxy)-ethoxy]-ethoxy}-ethoxy)-quinazoline-4,6-diamineHCID 90876776—

Reaction Steps

Compound 41b is prepared as described hereinabove for Compound 41a, using Compound 29b a starting material.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08461166B2
Source datasetuspto-grants-2013_06
ORD IDord-58172703720d428183bbe17194aaa254
Source noteuspto-grants-2013_06