HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroacetyl chloride → HCID 24960841, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroacetyl chloride | HCID 6577 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | HCID 24960475 | HCID 24960475 | — |
| Reactant | HCID 86618847 | HCID 86618847 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 24960841 | HCID 24960841 | — |
Reaction Steps
Compound 1c was prepared as described hereinabove for Compound 1a, using Compound 38c (0.13 gram, 0.21 mmol), DIPEA (0.43 mmol, 75.1 μl) and chloroacetylchloride (0.43 mmol, 34.3 μl in THF (18 ml), yielding 0.03 gram of the product (21% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08461166B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-56ed6d5451674a6d8d71a8c1b4757d1e |
| Source note | uspto-grants-2013_06 |