N,N-Dimethylpiperidin-4-amine → 1-(3-methoxy-4-nitrophenyl)-N,N-dimethylpiperidin-4-amine
Reaction equation
F[C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[C:4]([O:11][CH3:12])[CH:3]=1.[CH3:13][N:14]([CH3:21])[CH:15]1[CH2:20][CH2:19][NH:18][CH2:17][CH2:16]1>>[CH3:12][O:11][C:4]1[CH:3]=[C:2]([N:18]2[CH2:19][CH2:20][CH:15]([N:14]([CH3:21])[CH3:13])[CH2:16][CH2:17]2)[CH:7]=[CH:6][C:5]=1[N+:8]([O-:10])=[O:9]Participants
3
Procedure
Starting materials: 4-fluoro-2-methoxy-1-nitrobenzene and N,N-dimethylpiperidin-4-amine. m/z 280.
Sources & evidence
- ORD record
- ord-0b097ce6272a4815afd0cceb745f8cdf
- Source dataset
- uspto-grants-2013_06
- Patent number
- US08461170B2
Reaction notes
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