1-Methyl-4-(piperidin-4-yl)piperazine → 1-(1-(3-Methoxy-4-nitrophenyl)piperidin-4-yl)-4-methylpiperazine

HRID 1255997Notes

Reaction equation

HRID 1255997 reaction equation
F[C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[C:4]([O:11][CH3:12])[CH:3]=1.[CH3:13][N:14]1[CH2:19][CH2:18][N:17]([CH:20]2[CH2:25][CH2:24][NH:23][CH2:22][CH2:21]2)[CH2:16][CH2:15]1>>[CH3:12][O:11][C:4]1[CH:3]=[C:2]([N:23]2[CH2:22][CH2:21][CH:20]([N:17]3[CH2:16][CH2:15][N:14]([CH3:13])[CH2:19][CH2:18]3)[CH2:25][CH2:24]2)[CH:7]=[CH:6][C:5]=1[N+:8]([O-:10])=[O:9]

Participants

3

Reactant 2

HCID 7957071-Methyl-4-(piperidin-4-yl)piperazineHCID 27792505-Fluoro-2-nitroanisole

Product 1

HCID 567772491-(1-(3-Methoxy-4-nitrophenyl)piperidin-4-yl)-4-methylpiperazine

Procedure

Starting Materials: 4-fluoro-2-methoxy-1-nitrobenzene and 1-methyl-4-(piperidin-4-yl)piperazine.

Sources & evidence

ORD record
ord-6b275ed8615148ffba695166a3148de1
Source dataset
uspto-grants-2013_06
Patent number
US08461170B2

Reaction notes

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