4-(N-Boc-amino)piperidine → HCID 66710314, compound

HRID 1255998Notes

Reaction equation

HRID 1255998 reaction equation
F[C:2]1[CH:7]=[C:6]([O:8][CH3:9])[C:5]([N+:10]([O-:12])=[O:11])=[CH:4][C:3]=1[CH3:13].[NH:14]1[CH2:19][CH2:18][CH:17]([NH:20][C:21](=[O:27])[O:22][C:23]([CH3:26])([CH3:25])[CH3:24])[CH2:16][CH2:15]1>>[CH3:9][O:8][C:6]1[C:5]([N+:10]([O-:12])=[O:11])=[CH:4][C:3]([CH3:13])=[C:2]([N:14]2[CH2:15][CH2:16][CH:17]([NH:20][C:21](=[O:27])[O:22][C:23]([CH3:25])([CH3:24])[CH3:26])[CH2:18][CH2:19]2)[CH:7]=1

Participants

3

Reactant 2

HCID 7238334-(N-Boc-amino)piperidineHCID 184681411-Fluoro-5-methoxy-2-methyl-4-nitrobenzene2×

Product 1

HCID 66710314HCID 66710314, compound

Procedure

Starting Materials: 1-fluoro-5-methoxy-2-methyl-4-nitrobenzene (INTERMEDIATE 7) and tert-butyl piperidin-4-ylcarbamate.

Sources & evidence

ORD record
ord-4330df426a574f4b88ad12cf77843d42
Source dataset
uspto-grants-2013_06
Patent number
US08461170B2

Reaction notes

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