N,N-Dimethylpiperidin-4-amine → 1-(5-methoxy-2-methyl-4-nitrophenyl)-N,N-dimethylpiperidin-4-amine

HRID 1255999Notes

Reaction equation

HRID 1255999 reaction equation
F[C:2]1[CH:7]=[C:6]([O:8][CH3:9])[C:5]([N+:10]([O-:12])=[O:11])=[CH:4][C:3]=1[CH3:13].[CH3:14][N:15]([CH3:22])[CH:16]1[CH2:21][CH2:20][NH:19][CH2:18][CH2:17]1>>[CH3:9][O:8][C:6]1[C:5]([N+:10]([O-:12])=[O:11])=[CH:4][C:3]([CH3:13])=[C:2]([N:19]2[CH2:20][CH2:21][CH:16]([N:15]([CH3:22])[CH3:14])[CH2:17][CH2:18]2)[CH:7]=1

Participants

3

Reactant 2

HCID 417391N,N-Dimethylpiperidin-4-amineHCID 184681411-Fluoro-5-methoxy-2-methyl-4-nitrobenzene2×

Product 1

HCID 580714271-(5-methoxy-2-methyl-4-nitrophenyl)-N,N-dimethylpiperidin-4-amine

Procedure

Starting Materials: 1-fluoro-5-methoxy-2-methyl-4-nitrobenzene (INTERMEDIATE 7) and N,N-dimethylpiperidin-4-amine. m/z 294.

Sources & evidence

ORD record
ord-1ae1330f56244136878fb9733b6ac261
Source dataset
uspto-grants-2013_06
Patent number
US08461170B2

Reaction notes

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