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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1256005Generated: October 26, 2026

1-(Methylsulfonyl)piperazine → 1-{1-[3-(Methyloxy)-4-nitrophenyl]-4-piperidinyl}-4-(methylsulfonyl)piperazine

https://huagongshe.com/reaction/1256005

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(Methylsulfonyl)piperazineHCID 709161—
Reactant1-(3-Methoxy-4-nitrophenyl)piperidin-4-oneHCID 25918857—
Product1-{1-[3-(Methyloxy)-4-nitrophenyl]-4-piperidinyl}-4-(methylsulfonyl)piperazineHCID 59860245—

Reaction Steps

Starting materials: 1-(3-methoxy-4-nitrophenyl)piperidin-4-one (INTERMEDIATE 18) and 1-(methylsulfonyl)piperazine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08461170B2
Source datasetuspto-grants-2013_06
ORD IDord-ec5f1728c70747d7a1db1cb6f27d657e
Source noteuspto-grants-2013_06