2,6-Dimethylmorpholine, cis- → HCID 58071492, compound

HRID 1256008Notes

Reaction equation

HRID 1256008 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([N:12]2[CH2:17][CH2:16][C:15](=O)[CH2:14][CH2:13]2)[CH:6]=[CH:7][C:8]=1[N+:9]([O-:11])=[O:10].[CH3:19][C@@H:20]1[O:25][C@H:24]([CH3:26])[CH2:23][NH:22][CH2:21]1>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([N:12]2[CH2:17][CH2:16][CH:15]([N:22]3[CH2:21][C@@H:20]([CH3:19])[O:25][C@@H:24]([CH3:26])[CH2:23]3)[CH2:14][CH2:13]2)[CH:6]=[CH:7][C:8]=1[N+:9]([O-:11])=[O:10]

Participants

3

Reactant 2

HCID 6415002,6-Dimethylmorpholine, cis-HCID 259188571-(3-Methoxy-4-nitrophenyl)piperidin-4-one2×

Product 1

HCID 58071492HCID 58071492, compound

Procedure

Starting materials: 1-(3-methoxy-4-nitrophenyl)piperidin-4-one (INTERMEDIATE 18) and (2S,6R)-2,6-dimethylmorpholine. m/z 350.

Sources & evidence

ORD record
ord-56c4183028b744e5921b183074a28b93
Source dataset
uspto-grants-2013_06
Patent number
US08461170B2

Reaction notes

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