反应详情

3-Ethylaniline (2 g, 0.016 mol) was added slowly in portion into neat Ac2O (8 ml) at 0° C. After removed ice bath and the reaction was stirred at room temperature for 2 hour. The solvent was removed in vacuo and extracted with EtOAc, washed with water and brine, dried over Na2SO4. Concentrated to get crude N-(3-ethylphenyl)acetamide as light yellow solid.

1. customAfter removed ice bath
2. customThe solvent was removed in vacuo
3. extractionextracted with EtOAc
4. washwashed with water and brine
5. dry with materialdried over Na2SO4
6. concentrationConcentrated