Hydrochloric Acid → Methyl 3-aminophenylacetate

Participants

Reaction Steps

To a stirred solution of methyl 2-(3-nitrophenyl)acetate (7.3 g, 0.038 mol) and Fe (6.3 g, 0.113 mol) in MeOH (200 mL) was added concentrated HCl (20 mL). Then the mixture was stirred at room temperature over night. The mixture was filtered, the solvent was concentrated and the residue was dissolved in ethyl acetate and washed with brine, dried and concentrated to give the crude product of methyl 2-(3-aminophenyl)acetate (8.0 g, yield 97%).

Provenance & Evidence