HOAt → N-(4-Bromo-3-(4H-1,2,4-triazol-3-yl)thiophen-2-yl)-2-(2-(trifluoromethyl)quinolin-7-yl)acetamide
Reaction equation
[Br:19][c:20]1[c:21](-[c:26]2[n:27][n:28][cH:29][nH:30]2)[c:22]([NH2:25])[s:23][cH:24]1.[F:1][C:2]([c:3]1[n:4][c:5]2[cH:6][c:7]([CH2:13][C:14](=[O:15])[OH:16])[cH:8][cH:9][c:10]2[cH:11][cH:12]1)([F:17])[F:18].[OH:31][n:32]1[c:33]2[n:34][cH:35][cH:36][cH:37][c:38]2[n:39][n:40]1>>[F:1][C:2]([c:3]1[n:4][c:5]2[cH:6][c:7]([CH2:13][C:14](=[O:16])[NH:25][c:22]3[c:21](-[c:26]4[n:27][n:28][cH:29][nH:30]4)[c:20]([Br:19])[cH:24][s:23]3)[cH:8][cH:9][c:10]2[cH:11][cH:12]1)([F:17])[F:18]Participants
4
Sources & evidence
- ORD record
- ord-53c9fb2cd0eb410bbe953607ef15e113
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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