Ethyl 5-(chloromethyl)pyridine-2-carboxylate → 5-{3-Chloro-4-[3,3,3-trifluoro-2-hydroxy-1-methyl-2-(2-methyl-pyridin-4-yl)-propyl]-phenoxymethyl}-pyridine-2-carboxylic acid ethyl ester
Reaction equation
[CH2:24]([CH3:25])[O:26][C:27](=[O:28])[c:29]1[n:30][cH:31][c:32]([CH2:35][Cl:36])[cH:33][cH:34]1.[Cl:1][c:2]1[cH:3][c:4]([OH:23])[cH:5][cH:6][c:7]1[CH:8]([C:9]([C:10]([F:11])([F:12])[F:13])([c:14]1[cH:15][c:16]([CH3:20])[n:17][cH:18][cH:19]1)[OH:21])[CH3:22]>>[Cl:1][c:2]1[cH:3][c:4]([O:23][CH2:35][c:32]2[cH:31][n:30][c:29]([C:27]([O:26][CH2:24][CH3:25])=[O:28])[cH:34][cH:33]2)[cH:5][cH:6][c:7]1[CH:8]([C:9]([C:10]([F:11])([F:12])[F:13])([c:14]1[cH:15][c:16]([CH3:20])[n:17][cH:18][cH:19]1)[OH:21])[CH3:22]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-24624e1b0ae14e05b9a58d7ca283d186
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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