Hydrochloric Acid → HCID 86655982, compound

Participants

Reaction Steps

To a THF (11.8 mL) solution of the compound (590 mg) obtained in Step 50-1, concentrated HCl (8.9 mL) was added under ice cooling and the mixture was stirred at the same temperature for one hour. To the reaction mixture, a saturated K2CO3 was added and the solution was extracted with CHCl3. The organic layer was dried over MgSO4 and concentrated under reduced pressure to obtain (2-oxo-1,2,3,4-tetrahydroquinolin-7-yl)acetaldehyde (0.51 g, colorless amorphous).

Provenance & Evidence