Boronic Acid → HCID 44251382, compound

Participants

Reaction Steps

The titled compound was prepared using a procedure analogous to that described in connection with Example 15 except that N-(7-chloropyrazolo[1,5-a]pyrimidin-5-yl)-4-(2-hydroxypropan-2-yl)benzamide (2D) and the corresponding boronic acid or ester were used as starting material. The product was obtained a yellow solid (16%). 1H NMR (400 MHz, MeOD) δ ppm 1.57 (s, 6 H) 6.55 (d, J=2.27 Hz, 1 H) 7.57-7.63 (m, 3 H) 7.68 (d, J=8.59 Hz, 2 H) 7.99 (d, J=8.84 Hz, 2 H) 8.04-8.08 (m, 3 H) 8.09 (d, J=2.27 Hz, 1 H). ESI-MS: m/z 373.0 (M+H)+.

Provenance & Evidence