HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 3-[(Pyrrolidin-1-yl)methyl]benzoic acid hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Methyl 3-(pyrrolidin-1-ylmethyl)benzoate | HCID 53429637 | — |
| Product | 3-[(Pyrrolidin-1-yl)methyl]benzoic acid hydrochloride | HCID 18525874 | — |
Reaction Steps
A solution of 3-pyrrolidin-1-ylmethyl-benzoic acid methyl ester (800 mg, 3.6 mmol) in aqueous 25% hydrochloric acid (15 mL) was stirred at 90° C. for 4 hours. The solvent was evaporated affording the title compound as brown oil (quantitative) that was used as such for the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08461193B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-13aa797902c049a9a0a2029f555dbccb |
| Source note | uspto-grants-2013_06 |