2'-Methoxyacetophenone → 3-(4-Hydroxy-3,5-dimethylphenyl)-1-(2-methoxyphenyl)prop-2-en-1-one

HRID 1256696Notes

Reaction equation

[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[C:9](=[O:11])[CH3:10].[CH3:12][C:13]1[CH:14]=[C:15]([CH:18]=[C:19]([CH3:22])[C:20]=1[OH:21])[CH:16]=O>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[C:9](=[O:11])[CH:10]=[CH:16][C:15]1[CH:18]=[C:19]([CH3:22])[C:20]([OH:21])=[C:13]([CH3:12])[CH:14]=1

Participants

Reactant 2

HCID 684812'-Methoxyacetophenone

HCID 752223,5-Dimethyl-4-hydroxybenzaldehyde

Product 1

HCID 667043313-(4-Hydroxy-3,5-dimethylphenyl)-1-(2-methoxyphenyl)prop-2-en-1-one

Procedure

This compound was synthesized from 2′-methoxyacetophenone and 3,5-dimethyl-4-hydroxybenzaldehyde according to general method 1 described earlier.

Sources & evidence

ORD record: ord-2fe5bc4ee7294d578ae46d492ff470da
Source dataset: uspto-grants-2013_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08461212B2

Reaction notes

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