1H-Pyrrolo(2,3-b)pyridine → 3-((5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)methyl)-1H-pyrrolo[2,3-b]pyridine

HRID 1256768Notes

Reaction equation

HRID 1256768 reaction equation
[Cl:1][C:2]1[N:6]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[N:5]=[C:4]([CH3:13])[C:3]=1[CH:14]=O.[NH:16]1[C:24]2[C:19](=[CH:20][CH:21]=[CH:22][N:23]=2)[CH:18]=[CH:17]1>>[Cl:1][C:2]1[N:6]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[N:5]=[C:4]([CH3:13])[C:3]=1[CH2:14][C:18]1[C:19]2[C:24](=[N:23][CH:22]=[CH:21][CH:20]=2)[NH:16][CH:17]=1

Participants

3

Reactant 2

HCID 92221H-Pyrrolo(2,3-b)pyridineHCID 6130275-Chloro-3-methyl-1-phenyl-1H-pyrazole-4-carbaldehyde

Product 1

HCID 595933643-((5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)methyl)-1H-pyrrolo[2,3-b]pyridine

Procedure

3-((5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)methyl)-1H-pyrrolo[2,3-b]pyridine P-0080 was synthesized in 2 steps from 5-chloro-3-methyl-1-phenyl-1H-pyrazole-4-carbaldehyde 100 and 7-azaindole 1 as shown in Scheme 38.

Sources & evidence

ORD record
ord-aba1e6666c4442d0a0ce376fca80e700
Source dataset
uspto-grants-2013_06
Patent number
US08461169B2

Reaction notes

Loading…