HRID1256850

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(C)(C)OC(=O)N(Cc1cncc(F)c1)c1ccc(Br)c(F)n1

HCID57619177

未命名化合物

结构：CC(C)(C)OC(=O)N(Cc1ccc(Cl)cc1)c1ccc(Br)c(F)n1

HCID57619470

未命名化合物

PRODUCTS

生成物

结构：Fc1cncc(CNc2ccc(Cc3c[nH]c4ncccc34)c(F)n2)c1

HCID57619439

未命名化合物

PROCEDURE

实验过程

was prepared following the protocol of Scheme 201, replacing 5-bromo-6-fluoro-pyridin-2-yl)-(5-fluoro-pyridin-3-ylmethyl)-carbamic acid tert-butyl ester 631 with (5-Bromo-6-fluoro-pyridin-2-yl)-(4-chloro-benzyl)-carbamic acid tert-butyl ester 637 (prepared as described in Example 60) in Step 4. MS (ESI) [M+H+]+=391.9.

WORKUP

后处理

customwas prepared