Ethanol → HCID 44220653, compound

HRID 1256872Notes

Reaction equation

HRID 1256872 reaction equation
S(Cl)([Cl:3])=O.[CH2:5]([NH:7][CH2:8][C:9]([OH:11])=[O:10])[CH3:6].[CH2:12](O)[CH3:13]>>[ClH:3].[CH2:12]([O:10][C:9](=[O:11])[CH2:8][NH:7][CH2:5][CH3:6])[CH3:13]

Participants

4

Reactant 3

HCID 702EthanolHCID 24386Thionyl ChlorideHCID 316542N-Ethylglycine

Product 1

HCID 44220653HCID 44220653, compound

Procedure

To ethanol (30 mL) was added dropwise thionyl chloride (2.6 mL) at −10° C., and the mixture was stirred for 15 min. N-ethylglycine (1.0 g) was added to this solution at −10° C., and the mixture was allowed to warm to room temperature while stirring for 17 hr. The reaction mixture was concentrated under reduced pressure to give the title compound (1.63 g) as a white solid.

Workup

  1. stirringwhile stirring for 17 hr
  2. concentrationThe reaction mixture was concentrated under reduced pressure

Sources & evidence

ORD record
ord-09b434d36a8a429183b373b707cced9b
Source dataset
uspto-grants-2013_06
Patent number
US08461209B2

Reaction notes

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