HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl Malonate → Diethyl 2-(4-Methoxybenzyl)malonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl Malonate | HCID 7761 | — |
| Reactant | 4-Methyloxybenzyl chloride | HCID 69993 | — |
| Product | Diethyl 2-(4-Methoxybenzyl)malonate | HCID 232045 | 55.9% |
Reaction Steps
In the same manner as in Example 6 (1), a crude product was obtained using diethyl malonate (25.6 g) and 4-methoxybenzyl chloride (25.0 g). This was purified by silica gel column chromatography to give the title compound (25.0 g) as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08461209B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-0f7c91e646c94a6c9cc261f0c438fad5 |
| Source note | uspto-grants-2013_06 |