HCID 86645222, compound → HCID 86645221, compound

HRID 1256908Notes

Reaction equation

HRID 1256908 reaction equation
[CH2:1]([N:3]([CH2:24][CH3:25])[C:4](=[O:23])[CH:5]([CH2:20][C:21]#[CH:22])[C:6]([NH:8][S:9](/[CH:12]=[CH:13]/[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)(=[O:11])=[O:10])=[O:7])[CH3:2]>C(NC1C=CC=CC=1)C>[CH2:24]([N:3]([C:1]1[CH:21]=[CH:20][CH:5]=[CH:4][CH:2]=1)[C:4](=[O:23])[CH:5]([CH2:20][C:21]#[CH:22])[C:6]([NH:8][S:9](/[CH:12]=[CH:13]/[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)(=[O:10])=[O:11])=[O:7])[CH3:25]

Participants

3

Reactant 1

HCID 86645222HCID 86645222, compound

Product 1

HCID 86645221HCID 86645221, compoundYield 16.1%

Reagents, catalysts & solvents 1

HCID 7670N-EthylanilineSolvent

Procedure

In the same manner as in Example 1 (4), a crude product was obtained using the compound (1.04 g) obtained in Example 215 (2) and N-ethylaniline (430 μL). This was purified by silica gel column chromatography to give the title compound (95 mg) as a white powder.

Workup

  1. customThis was purified by silica gel column chromatography

Sources & evidence

ORD record
ord-36ed856b70e64024b38f655c8e111e41
Source dataset
uspto-grants-2013_06
Patent number
US08461209B2

Reaction notes

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