HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1E)-2-Phenylethenesulfonamide → 2-(4-cyanobenzyl)-3-oxo-3-[((E)-styrylsulfonyl)amino]propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1E)-2-Phenylethenesulfonamide | HCID 5357731 | — |
| Reactant | 2-(4-cyanobenzyl)-N,N-diethyl-N'-(2-naphthylsulfonyl)malonamide | HCID 86645217 | — |
| Product | 2-(4-cyanobenzyl)-3-oxo-3-[((E)-styrylsulfonyl)amino]propionic acid | HCID 68508236 | 176.7% |
Reaction Steps
In the same manner as in Example 152 (3), the object compound was obtained using the compound (1.57 g) obtained in Example 111 (2) and trans-β-styrenesulfonamide (1.25 g). This was subjected to hydrolysis in the same manner as in Example 1 (3) to give the title compound (2.30 g) as a white powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08461209B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-30f16c6891bc4aa09e6a7d8a89398718 |
| Source note | uspto-grants-2013_06 |