N-Ethylaniline → HCID 68508393, compound

HRID 1256917Notes

Reaction equation

HRID 1256917 reaction equation
[C:1]([CH2:3][CH2:4][CH:5]([C:13]([NH:15][S:16]([C:19]1[CH:28]=[CH:27][C:26]2[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=2)[CH:20]=1)(=[O:18])=[O:17])=[O:14])[C:6]([N:8]([CH2:11][CH3:12])[CH2:9][CH3:10])=[O:7])#[N:2].C(N[C:32]1[CH:37]=CC=[CH:34][CH:33]=1)C>>[C:1]([CH2:3][CH2:4][CH:5]([C:13]([NH:15][S:16]([C:19]1[CH:28]=[CH:27][C:26]2[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=2)[CH:20]=1)(=[O:17])=[O:18])=[O:14])[C:6]([N:8]([CH2:9][CH3:10])[C:11]1[CH:34]=[CH:33][CH:32]=[CH:37][CH:12]=1)=[O:7])#[N:2]

Participants

3

Reactant 2

HCID 7670N-EthylanilineHCID 86645226HCID 86645226, compound

Product 1

HCID 68508393HCID 68508393, compound

Procedure

In the same manner as in Example 1 (4), a crude product was obtained using the compound (1.00 g) obtained in Example 153 (3) and N-ethylaniline (379 μL). This was purified by silica gel column chromatography to give the title compound (687 mg) as a white powder.

Workup

  1. customThis was purified by silica gel column chromatography

Sources & evidence

ORD record
ord-7ae2d940e97f4783aafb2dab0002f245
Source dataset
uspto-grants-2013_06
Patent number
US08461209B2

Reaction notes

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