Benzenamine, 4-fluoro-N-(1-methylethyl)- → HCID 68506942, compound

HRID 1256920Notes

Reaction equation

HRID 1256920 reaction equation
[CH2:1]([N:8]([C:29]1[CH:34]=CC=C[CH:30]=1)[C:9]([C:11]1([C:15]([NH:17][S:18](/[CH:21]=[CH:22]/[C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)(=[O:20])=[O:19])=[O:16])[CH2:14][CH2:13][CH2:12]1)=[O:10])[C:2]1C=[CH:6][CH:5]=[CH:4][CH:3]=1.[F:35]C1C=CC(NC(C)C)=CC=1>>[F:35][C:4]1[CH:5]=[CH:6][C:1]([N:8]([CH:29]([CH3:34])[CH3:30])[C:9]([C:11]2([C:15]([NH:17][S:18](/[CH:21]=[CH:22]/[C:23]3[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=3)(=[O:19])=[O:20])=[O:16])[CH2:14][CH2:13][CH2:12]2)=[O:10])=[CH:2][CH:3]=1

Participants

3

Reactant 2

HCID 154403Benzenamine, 4-fluoro-N-(1-methylethyl)-HCID 68506242HCID 68506242, compound

Product 1

HCID 68506942HCID 68506942, compoundYield 7.6%

Procedure

In the same manner as in Example 1 (4), a crude product was obtained using the compound (1.00 g) obtained in Example 570 (1) and 4-fluoro-N-isopropylaniline (490 mg). This was purified by silica gel column chromatography to give the title compound (71 mg) as a white powder.

Workup

  1. customThis was purified by silica gel column chromatography

Sources & evidence

ORD record
ord-8f426caa538f4c879ef9d970f6486446
Source dataset
uspto-grants-2013_06
Patent number
US08461209B2

Reaction notes

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