HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Cyanide → gamma-Mangostin
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Cyanide | HCID 8929 | — |
| Reactant | Mangostin | HCID 5281650 | — |
| Reactant | beta-Mangostin | HCID 5495925 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | gamma-Mangostin | HCID 5464078 | — |
Reaction Steps
O-Methyl γ-mangostins such as β-mangostin, 3-O-methyl-γ-mangostin, 6,7-dimethyl-γ-mangostin and 3,6,7-trimethyl-γ-mangostin are conveniently converted to α-mangostin first by demethylation using sodium cyanide (NaCN) in dimethyl sulfoxide (DMSO) and then subjected to inventive O-demethylation process to obtain γ-mangostin in good yield and high purity.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08461360B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-9325fcc757fb4aa9b585513b335079f4 |
| Source note | uspto-grants-2013_06 |