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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 125718Generated: October 31, 2026

Pyridine → (3-Chloro-4-fluoro-phenyl)-[6-(4-chloromethyl-phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-amine

https://huagongshe.com/reaction/125718

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyridineHCID 1049—
ReactantTolueneHCID 1140—
ReactantThionyl ChlorideHCID 24386—
Reactant{4-[4-(3-Chloro-4-fluoro-phenylamino)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-phenyl}-methanolHCID 11234001—
Product(3-Chloro-4-fluoro-phenyl)-[6-(4-chloromethyl-phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-amineHCID 11383626—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-1ef42161223b499a82ad6390d37ba620
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)