2-Bromo-1-(3,4-dichlorophenyl)ethanone → HCID 58127750, compound

HRID 1257324Notes

Reaction equation

HRID 1257324 reaction equation
[NH2:1][C:2](=[S:15])[CH:3]([N:5]1[CH:9]=[C:8]([C:10]([O:12][CH2:13][CH3:14])=[O:11])[CH:7]=[N:6]1)[CH3:4].Br[CH2:17][C:18]([C:20]1[CH:25]=[CH:24][C:23]([Cl:26])=[C:22]([Cl:27])[CH:21]=1)=O>>[Cl:27][C:22]1[CH:21]=[C:20]([C:18]2[N:1]=[C:2]([CH:3]([N:5]3[CH:9]=[C:8]([C:10]([O:12][CH2:13][CH3:14])=[O:11])[CH:7]=[N:6]3)[CH3:4])[S:15][CH:17]=2)[CH:25]=[CH:24][C:23]=1[Cl:26]

Participants

3

Reactant 2

HCID 2447512-Bromo-1-(3,4-dichlorophenyl)ethanoneHCID 58127638HCID 58127638, compound

Product 1

HCID 58127750HCID 58127750, compoundYield 90.6%

Procedure

By a reaction in the same manner as in Example 1c and using the compound (227 mg, 1.00 mmol) obtained in Example 14b and 2-bromo-1-(3,4-dichlorophenyl)ethanone (268 mg, 1.00 mmol), the title compound (359 mg, 90%) was obtained as a colorless oil.

Workup

  1. customBy a reaction in the same manner as in Example 1c

Sources & evidence

ORD record
ord-12419c4a7e6544d2834c8641bf2c13dd
Source dataset
uspto-grants-2013_06
Patent number
US08461348B2

Reaction notes

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