ethyl 1-{[4-(3-nitrophenyl)-1,3-thiazol-2-yl]methyl}-1H-pyrazole-4-carboxylate → HCID 58127539, compound

Participants

Reaction Steps

To a mixed solution of the compound (3.15 g, 8.8 mmol) obtained in Example 25a in ethanol-tetrahydrofuran (v/v=1/1, 18 ml) was added Pd—C (10% wet., 320 mg), and the mixture was stirred at room temperature for 3 hr under a hydrogen atmosphere. Pd—C was removed, and the solvent was evaporated under reduced pressure to give a crude title compound (2.9 g).

Provenance & Evidence