反应详情

温度

80 °C

To a solution (9 mL) of the compound (2.0 g, 9.38 mmol) obtained in Example 1b in acetonitrile was added 3-bromo-2-oxopropanoic acid (1.9 g, 11.3 mmol), and the mixture was stirred at 80° C. for 2 hr. The resulting crystals were collected by filtration and washed with hexane to give the title compound (2.56 g, 97%) as pale-brown crystals.

1. filtrationThe resulting crystals were collected by filtration
2. washwashed with hexane