Water → HCID 66938994, compound

Participants

Reaction Conditions

Reaction Steps

To a mixed solution of the compound (2.2 g, 5.9 mmol) obtained in Example 89b in tetrahydrofuran/ethanol (v/v=1/1, 10 mL) was added sodium tetrahydroborate (340 mg, 8.9 mmol), and the mixture was stirred at 0° C. for 5 hr. Water was added to the reaction mixture, and the mixture was extracted with ethyl acetate. The obtained organic layer was washed with saturated brine, and dried over anhydrous sodium sulfate. The solvent was evaporated under reduced pressure. The resulting crude title compound was purified by column chromatography (hexane-hexane/ethyl acetate=50/50) to give the title compound (2.0 g, 92%) as a colorless oil.

Provenance & Evidence