ethyl 1-(2-tert-butoxy-2-oxoethyl)-1H-pyrazole-4-carboxylate → [4-(ethoxycarbonyl)-1H-pyrazol-1-yl]acetic acid

Participants

Reaction Steps

The compound (17.5 g) obtained in Example 115a was added to trifluoroacetic acid (280 mL), and the mixture was stirred at room temperature for 30 min. The reaction mixture was concentrated under reduced pressure, and the residue was washed with hexane, and dried to give the title compound (15.0 g) as a colorless solid.

Provenance & Evidence