HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl dithiophosphate, potassium salt → Methyl 4-[3-(3-bromophenyl)-1-carbamothioylpropyl]benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl dithiophosphate, potassium salt | HCID 1385274 | — |
| Reactant | Methyl 4-[3-(3-bromophenyl)-1-cyanopropyl]benzoate | HCID 66939300 | — |
| Solvent | Hydrogen chloride-ethyl acetate | HCID 21866389 | — |
| Product | Methyl 4-[3-(3-bromophenyl)-1-carbamothioylpropyl]benzoate | HCID 58127970 | 73% |
Reaction Steps
By a reaction in the same manner as in Example 178a and using the compound (3.94 g, 11.0 mmol) obtained in Example 181a, 4M hydrogen chloride-ethyl acetate solution (40 mL) and O,O-diethyl dithiophosphate (2.43 mL, 14.5 mmol), the title compound (3.15 g, 73%) was obtained as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08461348B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-e8e2bd8a64b24dacbdbeabc419a7f31a |
| Source note | uspto-grants-2013_06 |