2-Bromo-1-[3-(trifluoromethyl)phenyl]ethan-1-one → HCID 66939745, compound

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Reaction Steps

To a solution (4 mL) of the compound (400 mg, 1.7 mmol) obtained in Example 189c in ethanol was added 2-bromo-1-[3-(trifluoromethyl)phenyl]ethanone (530 mg, 2.0 mmol), and the mixture was heated under reflux overnight. The reaction mixture was allowed to cool to room temperature and the solvent was evaporated under reduced pressure. The obtained crude product was purified by recrystallization (ethyl acetate-hexane) to give the title compound (540 mg, 80%) as colorless crystals.

Provenance & Evidence