反应详情

A solution of the compound (0.45 g) obtained in Example 130b in dichloromethane (4 mL) was cooled in an ice bath, and Dess-martin reagent (0.94 g) was added. After stirring at room temperature for 1 hr, water was added to the reaction mixture, and the mixture was extracted with dichloromethane. The organic layer was washed with saturated aqueous sodium thiosulfate solution, dried over magnesium sulfate, and concentrated under reduced pressure to give a crude title compound.

1. extractionthe mixture was extracted with dichloromethane
2. washThe organic layer was washed with saturated aqueous sodium thiosulfate solution
3. dry with materialdried over magnesium sulfate
4. concentrationconcentrated under reduced pressure