Salicylic Acid → Aspirin

Participants

Reaction Steps

Reactor inlet stream 19 is in fluid communication with reactor 10. Reactor inlet stream 19 as introduced to reactor 10 comprises a molar excess of between about 2% and about 20% acetic anhydride compared to salicylic acid. Reactor 10 may preferably be any reactor configured for the esterification of reaction to produce acetyl salicyclic acid. Further, reactor 10 is preferably configured to distill acetyl salicylic acid. Reactor 10 may preferably be a continuous stirred tank reactor or a batch reactor, without limitation. Further, reactor 10 may preferably comprise a jacketed reactor. In certain embodiments, reactor 10 is configured as a holding tank for increased residence time, distillation, and/or agitation of reaction mixture.

Provenance & Evidence