HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → Oxane-4-carbonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | Oxane-4-carboxylic acid | HCID 219302 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | Oxane-4-carbonyl chloride | HCID 2795505 | — |
Reaction Steps
Oxalyl chloride (170 μL, 1.94 mmol) and DMF (2 drops) were added to a solution of tetrahydro-2H-pyran-4-carboxylic acid (84 mg, 0.64 mmol) in DCM (4 mL) and stirred for 1.5 hours. The reaction was concentrated under vacuum affording tetrahydro-pyran-4-carbonyl chloride. This was used with no further purification or analysis.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08461328B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-cd569e701fd84f6c93f17abfaf068b88 |
| Source note | uspto-grants-2013_06 |