HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1257930Generated: October 30, 2026
HCID 67223283, compound → HCID 67224078, compound
https://huagongshe.com/reaction/1257930
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | HCID 67223283 | HCID 67223283 | — |
| Reactant | Chloro(1-quinolin-6-ylcyclopropyl)acetaldehyde | HCID 86621504 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 67224078 | HCID 67224078 | — |
Reaction Steps
A mixture of 2-[4-(2-aminopyrimidin-5-yl)-2-fluorobenzoyl]aminopropanoic acid (0.20 g, 0.66 mmol) and chloro(1-quinolin-6-ylcyclopropyl)acetaldehyde (0.19 g, 0.79 mmol) in ethanol (4.0 mL) was stirred overnight at 90° C. The mixture was concentrated to afford the crude product. LCMS: (M+H)=496.1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08461330B2 |
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| Source dataset | uspto-grants-2013_06 |
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| ORD ID | ord-46d1259025114175b46958222f5d380b |
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| Source note | uspto-grants-2013_06 |
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