(Dimethyl sulfide)trihydroboron → HCID 57518698, compound

Participants

Reaction Steps

To a solution of step 5 intermediate (0.645 g, 2.66 mmol) in dry THF (10 mL) under N2 atmosphere, borane dimethylsulphide (0.328 mL, 3.46 mmol) was added slowly for 30 min through a septum and stirred for overnight. The reaction mixture was quenched with water, oxone then stirred for 30 mins. Then the reaction mixture was extracted with ethyl acetate, dried over sodium sulphate and concentrated under reduced pressure to afford the desired product (0.565 g) as colorless liquid. m/z (M+18): 246.

Provenance & Evidence