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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1258375Generated: October 30, 2026

Iodine → N-(3-iodo-4-hydroxynaphthalen-1-yl)thiophene-2-sulfonamide

https://huagongshe.com/reaction/1258375

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIodineHCID 807—
ReactantN-(3-bromo-4-hydroxynaphthalen-1-yl)thiophene-2-sulfonamideHCID 7718544—
ProductN-(3-iodo-4-hydroxynaphthalen-1-yl)thiophene-2-sulfonamideHCID 46909346100%

Reaction Steps

was prepared according to the procedure for 4b except using I2 solid. The reaction afforded title compound 129.4 mg (100%) as a brown solid, m.p.: 134-136° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08466157B2
Source datasetuspto-grants-2013_06
ORD IDord-3cc4bb9da5e3467d9f9aac187c045266
Source noteuspto-grants-2013_06