HRID1258391

反应详情

EQUATION

反应方程式

REACTANTS

反应物

$结构：O=C1C(Sc2ncn[nH]2)=C/C(=N\S(=O)(=O)c2cccs2)c2ccccc21$

HCID44654329

未命名化合物

结构：Cn1nnnc1Sc1cc(NS(=O)(=O)c2cccs2)c2ccccc2c1O

HCID135895396

未命名化合物

PRODUCTS

生成物

结构：O=S(=O)(Nc1cc(Sc2ncn[nH]2)c(O)c2ccccc12)c1cccs1

HCID2133817

未命名化合物

HCID135895396

未命名化合物

收率 100%

PROCEDURE

实验过程

N-(3-(1H-1,2,4-triazol-5-ylthio)-4-hydroxynaphthalen-1-yl)thiophene-2-sulfonamide (14e) was prepared according to the procedure for 14d except using (E)-N-(3-(1H-1,2,4-triazol-5-ylthio)-4-oxonaphthalen-1(4H)-ylidene)thiophene-2-sulfonamide (13e), which afforded the title compound 20 mg (100%) as a white solid, m.p.: 180° C. (dec.).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-b3dc6b6db04f48e4946e4fa9d7230149
来源数据集: uspto-grants-2013_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08466157B2
来源说明: uspto-grants-2013_06

反应 SMILES

[OH:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]([NH:12][S:13]([C:16]2[S:17][CH:18]=[CH:19][CH:20]=2)(=[O:15])=[O:14])=[CH:4][C:3]=1[S:21][C:22]1[N:26]([CH3:27])[N:25]=[N:24][N:23]=1.N1C(SC2C(=O)C3C(=CC=CC=3)/C(=N/S(C3SC=CC=3)(=O)=O)/C=2)=NC=N1>>[NH:23]1[C:22]([S:21][C:3]2[CH:4]=[C:5]([NH:12][S:13]([C:16]3[S:17][CH:18]=[CH:19][CH:20]=3)(=[O:15])=[O:14])[C:6]3[C:11]([C:2]=2[OH:1])=[CH:10][CH:9]=[CH:8][CH:7]=3)=[N:26][CH:27]=[N:24]1.[OH:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]([NH:12][S:13]([C:16]2[S:17][CH:18]=[CH:19][CH:20]=2)(=[O:15])=[O:14])=[CH:4][C:3]=1[S:21][C:22]1[N:26]([CH3:27])[N:25]=[N:24][N:23]=1