Acetyl chloride → HCID 58137441, compound

Participants

Reaction Steps

1-[2-Amino-4-(pentafluorosulfanyl)phenyl]ethanone (150 mg, example 19d) was dissolved in methylene chloride (5 ml). After adding triethylamine (95 μl) and acetyl chloride (51 μl), the mixture was stirred at RT for 4 h. Then methylene chloride, water and saturated sodium hydrogencarbonate solution were added. The organic phase was removed, washed three times with water, dried over magnesium sulfate, filtered and concentrated. 165 mg of the desired product were obtained.

Provenance & Evidence