HCID 58136914, compound → HCID 58136890, compound

Participants

Reaction Conditions

Reaction Steps

3-Ethoxy-N-methoxy-N-methyl-5-(pentafluorosulfanyl)benzamide (2.6 g) was dissolved in THF (60 ml). After cooling to 0° C., methylmagnesium bromide (6.46 ml, 3 M in ether) was added dropwise. Thereafter, the cooling bath was removed and stirring was continued at RT. After 1 h, the mixture was acidified with 1N hydrochloric acid, admixed with water and extracted by shaking twice with EA. The EA phases were dried over magnesium sulfate, filtered and concentrated. 2.25 g of the title compound were obtained.

Provenance & Evidence