化工社化工社 化学情報印刷レポート · 研究参考用
Methylamine → 4,5-Dichloro-n-methyl-2-nitroaniline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methylamine | HCID 6329 | — |
| 反応物 | 1,2-Dichloro-4-fluoro-5-nitrobenzene | HCID 533951 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 4,5-Dichloro-n-methyl-2-nitroaniline | HCID 289317 | — |
反応手順
1,2-Dichloro-4-fluoro-5-nitrobenzene (5.00 g, 23.8 mmol) in DMF (5.0 mL) was added to methylamine (10% in toluene, 80.0 g, 258 mmol) and stirred at rt overnight. The reaction mixture was filtered through a pad of ALOX B, washed with DMF/MeOH and concentrated to give the sub-title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08466186B2 |
| 出典データセット | uspto-grants-2013_06 |
| ORD ID | ord-d61c36bcae2d495787174dc822b42dd2 |
| 出典メモ | uspto-grants-2013_06 |