HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 3-Amino-2,4-dichlorobenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 1-Chloro-N,N-2-trimethylpropenylamine | HCID 640792 | — |
| Reactant | 3-Amino-2,4-dichlorobenzoic acid | HCID 15278234 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 3-Amino-2,4-dichlorobenzamide | HCID 58625467 | — |
Reaction Steps
(1-Chloro-2-methyl-propenyl)-dimethyl-amine (16.1 mL, 116 mmol) was added to 3-amino-2,4-dichloro-benzoic acid (20.0 g, 97.1 mmol) in THF (320 mL). After 4 h at rt the mixture was added dropwise to conc. NH3 (320 mL) and stirred at rt overnight. The reaction mixture was concentrated, cooled and filtered. The filtercake was dried to give the sub-title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08466186B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-73ba70766ac348d6b60ff348c1565a13 |
| Source note | uspto-grants-2013_06 |