Potassium Carbonate → HCID 67957967, compound

Participants

Reaction Conditions

Reaction Steps

Potassium carbonate (1.00 g, 7.3 mmol) was added to a mixture of pyrrolidine-2-carboxylic acid dimethylamide (1.00 g, 7.0 mmol) and 4,5-dichloro-2-nitroaniline (1.00 g, 4.8 mmol) in DMSO (6 mL). The reaction mixture was stirred at 120° C. for 2.5 h, diluted with EtOAc and washed with water and sat.aq. NaCl. The organic layer was dried over Na2SO4, concentrated and the crude was purified by chromatography to give the sub-title compound.

Provenance & Evidence