HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrahydrofuran → 5-Chloro-2-methylamino-4-morpholin-4-yl-aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | 4-Chloro-5-morpholin-4-yl-2-nitro-N-methyl-aniline | HCID 44120648 | — |
| Catalyst | Platinum | HCID 23939 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 5-Chloro-2-methylamino-4-morpholin-4-yl-aniline | HCID 67957652 | — |
Reaction Steps
The sub-title compound was prepared from (4-chloro-5-morpholin-4-yl-2-nitro-N-methyl-aniline (260 mg, 1.0 mmol), THF (6 mL), MeOH (6 mL) and Pt/C (50 mg) in analogy to example 1 step (f).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08466186B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-c69349b6f89b48afa50c4e88ff5823e9 |
| Source note | uspto-grants-2013_06 |